Dr Teoh – Family Medicine Specialist, Stem Cell & Immune Therapy

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Case Study: Chronic Low Back Pain, Slipped Disc, and Insomnia

2–3 minutes

Patient Profile:

  • Chronic low back pain due to a slipped disc
  • Suffering from chronic insomnia
  • Noted trigger point at the paraspinal muscle

Treatment Suggestion:

  • 100 million umbilical MSC therapy
  • MSC secretome injection at the trigger point

How Does This Approach Benefit the Patient?

Mesenchymal stem cell (MSC) therapy and MSC secretome injections offer a comprehensive solution to managing chronic low back pain, slipped discs, and insomnia. Here’s how:

Pain Relief and Disc Regeneration:

  • Inflammation Reduction: MSCs possess potent anti-inflammatory properties, which can help reduce inflammation around the slipped disc and paraspinal muscles. This reduction in inflammation can lead to significant pain relief.
  • Tissue Regeneration: MSCs can differentiate into various cell types, including nucleus pulposus-like cells, which are essential for the structural integrity of intervertebral discs. By promoting the regeneration of these cells, MSCs can help restore the disc’s function and prevent further degeneration.

Trigger Point Relief:

  • Localized Anti-inflammatory Effect: Injecting MSC secretome directly into the trigger point can modulate local inflammatory responses, reducing muscle tension and pain. The secretome contains bioactive molecules that promote healing and reduce inflammation at the injection site.
  • Muscle Healing: The bioactive components in the MSC secretome can aid in the repair of damaged muscle fibers, improving overall muscle function and reducing chronic pain associated with trigger points.

Improved Sleep:

  • Pain Management: By addressing the root cause of the pain, MSC therapy can significantly improve sleep quality. Pain is a common cause of insomnia, and effective pain management can lead to better rest and recovery.
  • Systemic Health Benefits: MSCs can enhance overall health by modulating immune responses and reducing systemic inflammation. These effects contribute to better sleep patterns and overall well-being.

References:

  1. Application of Stem Cells in the Repair of Intervertebral Disc Degeneration: Stem Cell Research & Therapy.
  2. Mesenchymal Stem Cell-Based Therapies for Treating Well-Studied Neurological Disorders: A Systematic Review: Frontiers.
  3. Clinical Application of Mesenchymal Stem Cell in Regenerative Medicine: A Narrative Review: Stem Cell Research & Therapy.
  4. Stem Cell Therapy for Chronic Pain Management: Cleveland Clinic.
  5. Stem Cell Therapy for Pain: An In-Depth Look: DVC Stem.
  6. Enhancement of the Therapeutic Efficacy of Mesenchymal Stem Cell Secretome in Treating Musculoskeletal Pain: Stem Cell Research & Therapy.

This comprehensive approach targets both the underlying causes of the patient’s pain and their secondary symptoms, offering a holistic path to recovery.