Dr Teoh – Family Medicine Specialist, Stem Cell & Immune Therapy

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Successful Treatment of Chronic Recurrent Left Achilles Tendinitis with MSC-Derived Secretome Injection

2–3 minutes

Introduction

Achilles tendinitis is a common condition that causes pain along the back of the leg near the heel. This condition often arises from overuse and can be very challenging to treat, especially in chronic cases. Today, we want to share a success story of a 52-year-old patient who suffered from chronic recurrent left Achilles tendinitis and found remarkable relief through an innovative treatment.

Case Background

Our patient had been experiencing chronic recurrent left Achilles tendinitis for an extended period. Traditional treatments, including nonsteroidal anti-inflammatory drugs (NSAIDs) and physiotherapy, had failed to provide any significant relief. The persistent pain and discomfort severely affected his daily activities and quality of life.

Turning Point: MSC-Derived Secretome Injection

In search of a more effective solution, we decided to try a local injection of MSC-derived secretome. One week after the treatment, the patient reported a complete cessation of pain, a result that had not been achieved with previous therapies.

How Does Secretome Work?

The secretome is a powerful component derived from mesenchymal stem cells (MSCs). It contains a rich mixture of growth factors, cytokines, and extracellular vesicles. Here’s how it works:

  1. Promotes Tissue Repair and Regeneration: The growth factors in the secretome help stimulate the repair and regeneration of damaged tissues.
  2. Reduces Inflammation: Cytokines within the secretome modulate the immune response, reducing inflammation which is a primary cause of pain in tendinitis.
  3. Enhances Natural Healing Processes: The extracellular vesicles facilitate communication between cells, enhancing the body’s natural healing mechanisms to repair the tendons.

Why Avoid Steroid Injections?

Steroid injections are commonly used to reduce inflammation and pain in tendinitis cases. However, they come with several potential downsides:

  1. Risk of Tendon Weakness: Long-term use of steroids can weaken the tendon, increasing the risk of rupture.
  2. Degenerative Changes: Repeated steroid injections can lead to degenerative changes in the tendon, further complicating the condition.
  3. Temporary Relief: Steroids do not promote true healing; they only mask the symptoms temporarily, which can lead to a recurrence of pain and inflammation.

Benefits of Secretome Injections

Choosing a secretome injection over steroid injections provides a more sustainable and regenerative approach to tendon healing. This treatment not only alleviates pain but also addresses the underlying issues, promoting true healing and reducing the likelihood of recurrence.

Conclusion

This case highlights the potential of MSC-derived secretome injections as a viable and effective treatment for chronic recurrent Achilles tendinitis. For patients who have not found relief through traditional methods, secretome therapy offers a promising alternative that promotes healing and restores quality of life.

Feel free to share your thoughts or experiences in the comments below. If you or someone you know is struggling with Achilles tendinitis, consider discussing secretome therapy with your healthcare provider.